¿SE CONOCE EL USO DE MELATONINA PARA EL CONTROL DE LA HIPSARRITMIA? O BIEN PARA EL CONTROL DE LAS CRISIS EN EL CASO DEL SINDROME DE WEST
Pregunta puesta por TETENIK

La melatonina se usa en pediatría con diversos fines, pero especialmente para tratar los problemas de sueño en los niños como alternativa a las benzodiacepinas. En el caso de problemas relacionados con el espectro autista el uso de la melatonina, aunque los estudios son pocos está documentado. Le remito a los artículos que puede encontrar en nuestra sección en la web.
Imagino su pregunta va orientada al uso de la melatonina en las crisis epilépticas, en este caso hay algo escrito, y recientemente se ha publicado un artículo al respecto:

Melatonin and sleep-related problems in children with intractable epilepsy.
Elkhayat HA, Hassanein SM, Tomoum HY, Abd-Elhamid IA, Asaad T, Elwakkad AS.

Department of Pediatrics, Ain Shams University, Cairo, Egypt.

Abstract
Children with epilepsy have high rates of sleep problems. Melatonin has been advocated in treatment of sleep disorders, and its beneficial effect has been confirmed in insomnia. The aim of this study was to assess melatonin levels in children with intractable epilepsy and its relation to pattern of sleep and characteristics of seizure disorder, as well as the effect of melatonin therapy on those parameters. The study was conducted on 23 children with intractable epilepsy and 14 children with controlled seizures. Patients were evaluated by psychometric sleep assessment and assay of diurnal and nocturnal melatonin levels. Children with intractable epilepsy received oral melatonin before bedtime. They were reassessed after 3 months. Children with intractable epilepsy had higher scores for each category of sleep walking, forcible teeth grinding, and sleep apnea. At the end of therapeutic trial, patients with intractable epilepsy exhibited significant improvement in bedtime resistance, sleep duration, sleep latency, frequent nocturnal arousals, sleep walking, excessive daytime sleepiness, nocturnal enuresis, forcible teeth grinding, sleep apnea, and Epworth sleepiness scores. There was also significant reduction in seizure severity. Thus, use of melatonin in patients with intractable seizures was associated with improvement of both many sleep-related phenomena and the severity of seizures. Copyright 2010 Elsevier Inc. All rights reserved.



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